Acute Promyelitic Leukemia: Molecular Genetics, Mouse Models by Pier Paolo Pandolfi,Peter K. Vogt

By Pier Paolo Pandolfi,Peter K. Vogt

during the last 10 years, paintings on acute promyelocytic leukemia (APL) has turn into the paradigm of translational study that all started with the invention of a recurrent chromosomal translocation, via the identity of the genes and proteins concerned, discovering their molecular features in transcriptional keep an eye on, setting up mouse types and culminating within the improvement  of designated therapy.

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